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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1012a7dd3f03bd68fc1e28569f845450bbcfe3d252eefb98f86d8e05dd6405df' 
  AND token = 'HqDHgjsnZ+VLSOndz31dush5e7M7AVoYbaV8yZ/nbrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}