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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b8c4463e0e2520aa6f08ce94ded863b01b2f669b0f8974d7d287e1a0f59933d' 
  AND token = 'BtZoyoELEEs7W80syX+/lPHC3uE4JgvT8nup5K7HO8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}