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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d86ef30e126a2844f6ad561f999d09138b5a9a71cc540da123b7cfca6d0ed05' 
  AND token = 'drV6RTmT2aGwjY16m91Qv4mPlj7PrWanAsrAy0XeIwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}