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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a978980fce6775504292cf9f23225d27913cb18be292ec412de3ba0b3b859fa2' 
  AND token = 'vU2PaCTTZbMU+s12CeRUAXOs6UcC0Hdg7dZ35GfDPa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}