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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0b6b2bf0dbb7ceff5961ddc7b5849b8eea093fa9bb0e1501ad13fceaa32da72' 
  AND token = 'oPDIc4MAuu01+IK0kTCW2OhYuHw3WKAjC7g76IrHvWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}