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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75fd75017ebb142a4f02a10ec7bf4d4fd8d097ae148125712001c9064a03e98' 
  AND token = '44zLNVug8uZg/VSks9ZHx7H+6fL15b5gqIuK581ohHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}