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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c4c3660abea2eba6ac80e990b9763105ec92534e9a6b2717a7e4a267cfaabb4' 
  AND token = 'eEmXV5t+Iff+kDj0xhN1TbnbO1A8wxcrFLjiiWvdvuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}