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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b5608ed5d5e8c6a12835bc5602697b8264d3d53c315a1b78cfe7cdbe50a06d0' 
  AND token = 'IAftGxp0qQRlnuj/U8L65gWo3Wcq+n5QJTqoAFrP/Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}