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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d481cbfc08ad52dcbb2deed6671a273460d05ff03889c63b8297ea8f1f6ccdc' 
  AND token = 'Qhxa6JWMb3ZhvRV0+nmXRML4xteg8E7F1fIRNLTT3KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}