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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b1bc66630ea36b1f783fd8976c2e660ed7d4fdf0b2aaef4a15d14931d2b0a25' 
  AND token = 'yZWfT9WSn1t+/j8JutMpTC1bk4qjq9J5ewM+UYpriMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}