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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075ddedbf95c49a26e53833a8f7649902b2a4a1898fb7f9c0d14848bad85d4e3' 
  AND token = 'QOQfjzi1Fu6tJxXs+0kZYPekO6N+rVC3jnV8mR6v2u4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}