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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3c31700b8a25d046a84967758409b79c4b5268815fb07928907a92ea1b4868' 
  AND token = 'yMatoiNUGz7FgyDvduCuX26uTzN3znuWiVt4lVHYIvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}