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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ece5eea8f7d0d45955d402fb1237287f18c16071ba4b8701f4f778548ef819d' 
  AND token = '5yxD6XR+II+zzWZ9R27+RVdhmK+zCLNPIm0jXsR5aWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}