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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb7a185dc1865fe9a66d98b60500c9b86ca123f7e91c5c91edee91a386bac85' 
  AND token = 'bJm60x5RaVdGux4jS+TcDdRZEqOQvqYjhpSh3UCAKCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}