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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f921b2bb9d5ae611be033fc41ea01d7f052e439790777113874e70bb6d878df' 
  AND token = 'vQPDZBnJbAii7Q+pPl05iIAxMY/USvrn4w0U8QCFDIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}