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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7000ffc6eeccddbe2b48d85c76d7002b0201f8ec9a9038d846535bb78e5a81' 
  AND token = 'hnn5c1BYK4xtO2pvL63w7Gx/DePLSHrEj5+yZK5C2bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}