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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074f2c45d7ecf72f958414576a0b639c8c1ad566f317dccec33bed6c1b13ac90' 
  AND token = 'f0fOp6SNs91ZA+VSI21yKha7tZ+fjDit+bheMsRituo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}