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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5762f4b76505ef8f0eb9200b90e34504d4e9f8e160f11a551975217b91758d' 
  AND token = 'NAeSVrCeS0h1Ml3GWX8+sU3Eor6rke1QuzhpBlZSQOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}