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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05383d916ef06d5d0f6ebc0c2678133104cc4b38dd6b8b66a5b5a52fe815e2d' 
  AND token = 'l48Ms2ScG/Fvlv/65CC+SIRJ6RrHR99DT6bKou89Fz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}