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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb20afa88f9080eab7412cc65796ee52df81497bd5ba8bfb028873c4460f9a8' 
  AND token = 'pcsIQ8sNNMP73OUBK4KhFgFPgLp+yREwE51uc1JW814=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}