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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a8c0cada65b5d94f9fbfd595d92c28c5b3f0e450a807ca7844d908415d100e' 
  AND token = 'PAOlrCoo79URhXUrO/ShzDrKk9CnQ15UwR5vtZ+wnn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}