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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fca72c644dc0a545ea573a0ad67d998f86e513b7d03486abe730fa638f47350' 
  AND token = 'Pu6VFUIP5Z4aiHxP+O3t82guCGRTCoIDA28DrGb5uM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}