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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '534348cd160544d2216132d5cbc011e9612fdef7ea1e8a78feaa341cbd148024' 
  AND token = 'u+FvMZGlMcGWiKhl+UI+08QevRSe+wQ6TvL3NQWWnrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}