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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647a7a15db005b04f3875b705448a55bc79dc7079cf6651bcd3be2b6ca183ecb' 
  AND token = 'llxqS8IHmRRWcwd+TtgOEOn5v7bqiQGIXgGoDf/w1wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}