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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05dcbf47394af297230e153b19e7477d93043aa373dd522dba10758778321b35' 
  AND token = '1CAWDX4xktB1Zwjqu06y8WfReZa6WEdzew+QaD/Ev28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}