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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b683f21b2b5d010874ad3ae59295f7228229a84d2e446903a002c705929bc87b' 
  AND token = 'xdYmfPaqCN+zo4W5njpLsKtYEcaNW3th0+Fd5lD6yAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}