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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e26a05fd4a3aa6e07518e5afd1a4ffb641d5b76200f99303418ea73dcf1409b6' 
  AND token = 'aa8FVgX/uWFrNI9sXoU530sxIhOkikJbijp6RhI2axQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}