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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b680de2cfc41d032f23ebde2c6090df2d191abc8e45ab5242d3fc64202645c15' 
  AND token = '3kIkxCrYftItHNsBl9LYpJmM8abaaa+f1ja65v75Xv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}