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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70c088d0115d31be858d273e1f5c728f7a364af47ac6a3851f82252f6a0e38be' 
  AND token = 'K6fwqMZyiOh+YnF42bd63h27XKHLSp7PJl6hvNENiIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}