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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d18b4cf1983e0e7263fffe9b3a4016f6f306d8648a8bab9a3b79fba23f2e80f' 
  AND token = 'tB8JPiiF9Weh/rw44rrw5Dru3Y3Uv7P+uhzKd0HwVrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}