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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863a5be4348c8cbc0ac8f5f8df946a73148d0225f5d3f21585c27c7670af241a' 
  AND token = 'GyyWL35Wj5UnDxeVjbqgS5D0FgomnRLgwoaySM1H6OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}