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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d57cfb06e3c6297c3e15d919461548a21bd9bddb27c40c4f70b409efcc2e2bd' 
  AND token = '9S/IAg5HYtOyAzEuRnclsUyyX2Yr3qj4JQ6FtEBc230=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}