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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38eece8b16647b9c31d7b5d446bb0900ecbd8963ae73905ea267f2783a68ea0c' 
  AND token = 'N0SyYNC2Xh2javOZnP21swl5FoYVIr3TU/o2EnxKFGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}