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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a9746c43b6fcccb25c6d07ac9cf982725098a372dfb26c19e72993a7ba9af0c' 
  AND token = 's3eFKWwAq5j2q/L+PYXqjLQGxFIdqspwlKZLswtLHts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}