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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9183290f183f33f54ac141de04de32facb9d1070ec04e8573a48790a4e5c9c' 
  AND token = 'w1JgqlCQQsWjAP8H7TyOMNe/UAlqfI5/TPyIbW2iP6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}