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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0453ff63efdf13bf442b2316ee55af6a832d6d4960fc484d0fc2b95a8e7f1dc0' 
  AND token = 'sYtEhtFp+9vc5MW9J/293VlxAKSErMy+Wivm+kY2L44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}