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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc6c1670270d86348dae6c4d4dce897402ad36809f90e155c808587eb4f291aa' 
  AND token = 'w7QJL7gdXG9J6T5i3/eoTf/ZsIzX1nlFUA9CjBzUboo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}