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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '717d58a518eedc1baeab573bbcf984395f856c0f304814978a5e0324c7262f35' 
  AND token = 'p3XPMD+TKRKcPl4Bjkybb+OZH8WFoifTEQNGIy31Ea4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}