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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ecc8d2c35703970a9f1fdac522c9eb135d8a93af5292d7c36dec4e5045be5eb' 
  AND token = 'TzJxpPjQeGJxX1qBYABuW2LC7A/0cZ/4b0Xs8Yj9tsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}