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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57050f85e5ccbab20a2342c758292762734e2a3d5d1cc90b35a7300d16161a09' 
  AND token = 'bWvVAKrsOoq8Su7QwviNt5y6z3UPBW1s2vmmVNxN9Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}