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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34b6f8560f8a4028f7349085edcbaf9027966775d8e2aa2cc3f21c8510376971' 
  AND token = 'Mz/4SKHlGC95BnRFCZ6HS0zXmZke3UT+iYldd0wSeeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}