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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'faa1d2a560e4e0b12dce35e471a43fad1fd6ac3fc1d7ff9a07953cf019438268' 
  AND token = 'BxnzmqvOh66X9dqGcDoDuPl4+sO+fJkS2nATwwyIQr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}