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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de704bdbc24e70ced490825c3f80e0339dcc252e79dee725be8e547d30d7ac5' 
  AND token = 'ZjK8GdcWF/E4uGyIUNM1oDMv8BZO/cByJbSuQy7HpmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}