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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1204aad8efdb03c7ff1d74d2fe6c1acfb6f87d11a509d2b1556f7e478c437007' 
  AND token = 'da+TKOYUWwG5Adw26Q9L/Ig79XKLKLS1tr52HvmwQuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}