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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfc4bc058639f6f7cde22e9c765d35404ac5665ada5c50996420db18e73bb569' 
  AND token = '0yQgHyrtFSwn4cSZH3UWD5YrLFPkP6iZNHP/93cLQv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}