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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c566a168f79628426c4c6ef0384ea266d446f228f1fa002622756cdbd2274b95' 
  AND token = 'dDNTI8hwokIOHxQVzowd/R3aP/R4HAFaykvzy4R2GTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}