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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f06a06c68aea2e391d2cef330475ac3b2ac3481bbc06a58e77bf76e89b051f87' 
  AND token = '3GsJxOyk9bIMfTOuMTq64eyLsn1CaE1xJP0EVgZCWdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}