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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79ce1e04d9cca2a7448ebf86530c6350a40430b7910f2759466dfee0f725b110' 
  AND token = 'wD03m7USfXnk/BSGCUeJeIjXlL/H2y2+C+Ke9hXMy0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}