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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339cb133064eb3ef1282b6cb7e349ef975184c5ff706510eafe2d6046f4a0294' 
  AND token = 'iHIBFfI0wMCW8ei34qPm7vx5LPFrUDTutsXW6CUza/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}