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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a75aea55df3b1b826b3294987cad459c2fcce51722e155385c5c52a39b071a3e' 
  AND token = 'NW+g7VFbM5hCX9EEteV5bwPw1hpgInoSXvkZsfsW8jE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}